Research progress of receptor tyrosine kinase AXL in tumor / 实用肿瘤学杂志

AXL is a member of the TAM receptor tyrosine kinase family,and AXL has been shown to beassociated with a variety of cancers such as lung cancer,breast cancer,thyroid cancer,prostate cancer and pancre-atic cancer.The latest evidence suggests that AXL can promote the growth,invasion and metastasis of varioustumors,and its inhibitors can also inhibit tumor formation,suggesting that AXL may be a potential target for anti-tumor therapy,and the use of AXL kinase inhibitors may become the new strategy of anti-tumor therapy.This ar-ticle reviews the progress of AXL and tumor.